Mathieu JM Bertrand studied bioengeneering at the University of Louvain (UCL), and did his PhD on the functional characterisation of the MAGE genes in the lab of Prof. De Backer at the Ludwig Institute for Cancer Research (LICR) and University of Namur. He then moved to the lab of Prof. Barker at McGill University for a first postdoctoral training during which he studied regulation of innate immune signalling by ubiquitylation. He later joined the lab of Prof. Vandenabeele at the Vlaams Instituut voor Biotechnologie (VIB) and Ghent University for a second postdoc on the regulation of cell death signalling by postranslational modifications. He was appointed with a professor position at Ghent University in 2011, and since then leads a research team at the VIB-UGent Center for Inflammation Research (IRC). Research in his lab aims at characterising the interplay between cell death and inflammation, and at defining the role of cell death in the context of infection and inflammatory pathologies. The lab has expertise in the elucidation and characterisation of the molecular mechanisms regulating cell survival/death and inflammatory responses downstream of TNF receptor superfamily members and pattern recognition receptors. The lab recently got very interested in the role of autophagy in the various aspects of the inflammatory response.